Cargando…

Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis()

Medulloblastoma is the most common malignant brain tumor in children. Therapeutic approaches to medulloblastoma (combination of surgery, radiotherapy, and chemotherapy) have led to significant improvements, but these are achieved at a high cost to quality of life. Alternative therapeutic approaches...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Tao, Zhang, Honglai, Park, Sung-Soo, Venneti, Sriram, Kuick, Rork, Ha, Kimberly, Michael, Lowell Evan, Santi, Mariarita, Uchida, Chiyoko, Uchida, Takafumi, Srinivasan, Ashok, Olson, James M., Dlugosz, Andrzej A., Camelo-Piragua, Sandra, Rual, Jean-François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2017
Materias:	Short communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293723/ https://www.ncbi.nlm.nih.gov/pubmed/28167297 http://dx.doi.org/10.1016/j.neo.2017.01.002

Ejemplares similares

Loss of AMPKα2 Impairs Hedgehog-Driven Medulloblastoma Tumorigenesis
por: Zhang, Honglai, et al.
Publicado: (2018)

Prolyl Isomerase Pin1 Protects Mice from Endotoxin Shock
por: Akiyama, Hirotada, et al.
Publicado: (2011)

Prolyl Isomerase Pin1 Directly Regulates Calcium/Calmodulin-Dependent Protein Kinase II Activity in Mouse Brains
por: Shimizu, Taiki, et al.
Publicado: (2018)

Brown Algae Polyphenol, a Prolyl Isomerase Pin1 Inhibitor, Prevents Obesity by Inhibiting the Differentiation of Stem Cells into Adipocytes
por: Suzuki, Atsuko, et al.
Publicado: (2016)

Prolyl Isomerase Pin1 Regulates Mouse Embryonic Fibroblast Differentiation into Adipose Cells
por: Uchida, Takafumi, et al.
Publicado: (2012)

Multiple system atrophy pathology is associated with primary Sjögren’s syndrome
por: Conway, Kyle S., et al.
Publicado: (2020)

BRAF activating mutations involving the β3-αC loop in V600E-negative anaplastic pleomorphic xanthoastrocytoma
por: Pratt, Drew, et al.
Publicado: (2018)

H3K27M-mutant diffuse midline glioma with extensive intratumoral microthrombi in a young adult with COVID-19-associated coagulopathy
por: Pun, Matthew, et al.
Publicado: (2020)

Targeting the Hedgehog Pathway in Pediatric Medulloblastoma
por: Huang, Sherri Y., et al.
Publicado: (2015)

Prolyl Isomerase, Pin1, Controls Meiotic Progression in Mouse Oocytes
por: Hoshino, Yumi, et al.
Publicado: (2022)

Circular RNAs in Hedgehog Signaling Activation and Hedgehog-Mediated Medulloblastoma Tumors
por: Azatyan, Ani, et al.
Publicado: (2021)

Decoding the Roles of Astrocytes and Hedgehog Signaling in Medulloblastoma
por: Duarte, Terence Teixeira, et al.
Publicado: (2021)

Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis
por: Infante, Paola, et al.
Publicado: (2018)

Genetic drivers of metastatic dissemination in sonic hedgehog medulloblastoma
por: Jenkins, Noah C, et al.
Publicado: (2014)

HDL nanoparticles targeting sonic hedgehog subtype medulloblastoma
por: Bell, Jonathan B., et al.
Publicado: (2018)

Sonic Hedgehog-Induced Histone Deacetylase Activation Is Required for Cerebellar Granule Precursor Hyperplasia in Medulloblastoma
por: Lee, Seung Joon, et al.
Publicado: (2013)

Survivin as a therapeutic target in Sonic hedgehog-driven medulloblastoma
por: Brun, Sonja N., et al.
Publicado: (2014)

Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells
por: Scheidt, Tamara, et al.
Publicado: (2020)

MBCL-21. GERMLINE ELONGATOR MUTATIONS IN SONIC HEDGEHOG MEDULLOBLASTOMA
por: Robinson, Giles W, et al.
Publicado: (2020)

Liposome-Imipramine Blue Inhibits Sonic Hedgehog Medulloblastoma In Vivo
por: MacDonald, Tobey J., et al.
Publicado: (2021)

Drug Delivery Systems for Hedgehog Inhibitors in the Treatment of SHH-Medulloblastoma
por: Caimano, Miriam, et al.
Publicado: (2021)

Clinical and molecular analysis of smoothened inhibitors in Sonic Hedgehog medulloblastoma
por: Pereira, Victor, et al.
Publicado: (2021)

Generating a mouse model for relapsed Sonic Hedgehog medulloblastoma
por: Heller, Allie, et al.
Publicado: (2023)

Sonic hedgehog signaling: Alternative splicing and pathogenic role in medulloblastoma
por: Qu, Meiyu, et al.
Publicado: (2022)

Trp53 null and R270H mutant alleles have comparable effects in regulating invasion, metastasis and gene expression in mouse colon tumorigenesis
por: Tang, Jinyu, et al.
Publicado: (2019)

Kir2.1 Interactome Mapping Uncovers PKP4 as a Modulator of the Kir2.1-Regulated Inward Rectifier Potassium Currents
por: Park, Sung-Soo, et al.
Publicado: (2020)

Dual role of the integrated stress response in medulloblastoma tumorigenesis
por: Stone, Sarrabeth, et al.
Publicado: (2016)

The role of microRNAs during the genesis of medulloblastomas induced by the hedgehog pathway
por: Luo, Xiaoju, et al.
Publicado: (2011)

The Ketogenic Diet Does Not Affect Growth of Hedgehog Pathway Medulloblastoma in Mice
por: Dang, Mai T., et al.
Publicado: (2015)

A Sexually Dimorphic Role for STAT3 in Sonic Hedgehog Medulloblastoma
por: White, Christine L., et al.
Publicado: (2019)

A novel role of HLA class I in the pathology of medulloblastoma
por: Smith, Courtney, et al.
Publicado: (2009)

YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog - dependent cerebellar granule neuron progenitor cells and medulloblastoma cells
por: Dey, Abhinav, et al.
Publicado: (2016)

SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development
por: Raducu, Madalina, et al.
Publicado: (2016)

Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma
por: Maximov, Victor, et al.
Publicado: (2019)

Upregulation of the chromatin remodeler HELLS is mediated by YAP1 in Sonic Hedgehog Medulloblastoma
por: Robinson, M. Hope, et al.
Publicado: (2019)

Nilotinib, an approved leukemia drug, inhibits smoothened signaling in Hedgehog-dependent medulloblastoma
por: Chahal, Kirti Kandhwal, et al.
Publicado: (2019)

MAPK15 Controls Hedgehog Signaling in Medulloblastoma Cells by Regulating Primary Ciliogenesis
por: Pietrobono, Silvia, et al.
Publicado: (2021)

MEDB-57.GNAS inactivation as a driver for sonic hedgehog-activated medulloblastoma
por: Goode, Erin, et al.
Publicado: (2022)

Effects of metformin on Sonic hedgehog subgroup medulloblastoma progression: In vitro and in vivo studies
por: Fang, Huangyi, et al.
Publicado: (2022)

KMT2D suppresses Sonic hedgehog-driven medulloblastoma progression and metastasis
por: Sanghrajka, Reeti Mayur, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_fglasl3mg7hrf5vcu4edsiac1j