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GTPase of the Immune-Associated Nucleotide Protein 5 Regulates the Lysosomal Calcium Compartment in T Lymphocytes

T lymphocytes from Gimap5(lyp/lyp) rats carrying a recessive mutation in the GTPase of immune-associated protein 5 (Gimap5) gene undergo spontaneous apoptosis. Molecular mechanisms underlying this survival defect are not yet clear. We have shown that Gimap5(lyp/lyp) T lymphocytes display reduced cal...

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Detalles Bibliográficos
Autores principales:	Serrano, Daniel, Ghobadi, Farnaz, Boulay, Guylain, Ilangumaran, Subburaj, Lavoie, Christine, Ramanathan, Sheela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293772/ https://www.ncbi.nlm.nih.gov/pubmed/28223986 http://dx.doi.org/10.3389/fimmu.2017.00094

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