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Diversity and Recognition Efficiency of T Cell Responses to Cancer

BACKGROUND: Melanoma patients vaccinated with tumor-associated antigens frequently develop measurable peptide-specific CD8+ T cell responses; however, such responses often do not confer clinical benefit. Understanding why vaccine-elicited responses are beneficial in some patients but not in others w...

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Detalles Bibliográficos
Autores principales: Stuge, Tor B, Holmes, Susan P, Saharan, Sahdev, Tuettenberg, Andrea, Roederer, Mario, Weber, Jeffrey S, Lee, Peter P
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC529423/
https://www.ncbi.nlm.nih.gov/pubmed/15578105
http://dx.doi.org/10.1371/journal.pmed.0010028