The Nedd8 Non-covalent Binding Region in the Smurf HECT Domain is Critical to its Ubiquitn Ligase Function

Nedd8 is a ubiquitin-like protein that controls vital biological events through conjugation to target proteins. We previously identified the HECT-type ubiquitin ligase Smurf1 which controls diverse cellular processes is activated by Nedd8 through covalent neddylation. However, the effect of non-cova...

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Detalles Bibliográficos
Autores principales: He, Shan, Cao, Yu, Xie, Ping, Dong, Guanglong, Zhang, Lingqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294409/
https://www.ncbi.nlm.nih.gov/pubmed/28169289
http://dx.doi.org/10.1038/srep41364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294409/
https://www.ncbi.nlm.nih.gov/pubmed/28169289
http://dx.doi.org/10.1038/srep41364

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