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Enhancement of 5-aminolevulinic acid-based fluorescence detection of side population-defined glioma stem cells by iron chelation

Cancer stem cells (CSCs) are dominantly responsible for tumor progression and chemo/radio-resistance, resulting in tumor recurrence. 5-aminolevulinic acid (ALA) is metabolized to fluorescent protoporphyrin IX (PpIX) specifically in tumor cells, and therefore clinically used as a reagent for photodyn...

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Detalles Bibliográficos
Autores principales:	Wang, Wenqian, Tabu, Kouichi, Hagiya, Yuichiro, Sugiyama, Yuta, Kokubu, Yasuhiro, Murota, Yoshitaka, Ogura, Shun-ichiro, Taga, Tetsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294410/ https://www.ncbi.nlm.nih.gov/pubmed/28169355 http://dx.doi.org/10.1038/srep42070

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