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Novel benzoxazole derivatives DCPAB and HPAB attenuate Th1 cell-mediated inflammation through T-bet suppression

Interferon-γ (IFN-γ), a critical inflammatory cytokine, is primarily produced by T helper 1 (Th1) cells and accelerates the pathogenesis of inflammatory colitis. Pharmacological suppression of IFN-γ production attenuates dysregulated inflammatory responses and may be beneficial for treating inflamma...

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Detalles Bibliográficos
Autores principales:	Oh, Yeon Ji, Kim, Darong, Oh, Sera, Jang, Eun Jung, Won, Hee Yeon, Jeong, Hana, Jeong, Mi Gyeong, Choo, Hea-Young Park, Hwang, Eun Sook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294415/ https://www.ncbi.nlm.nih.gov/pubmed/28169371 http://dx.doi.org/10.1038/srep42144

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