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Novel peptides for deciphering structural and signalling functions of E-cadherin in mouse embryonic stem cells

We have previously shown that E-cadherin regulates the naive pluripotent state of mouse embryonic stem cells (mESCs) by enabling LIF-dependent STAT3 phosphorylation, with E-cadherin null mESCs exhibiting over 3000 gene transcript alterations and a switch to Activin/Nodal-dependent pluripotency. Howe...

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Detalles Bibliográficos
Autores principales:	Segal, Joe M., Ward, Christopher M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294416/ https://www.ncbi.nlm.nih.gov/pubmed/28169326 http://dx.doi.org/10.1038/srep41827

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