Cargando…

Integrative analysis of copy number and transcriptional expression profiles in esophageal cancer to identify a novel driver gene for therapy

An increasing amount of evidence has highlighted the critical roles that copy number variants play in cancer progression. Here, we systematically analyzed the copy number alterations and differentially transcribed genes. Integrative analysis of the association between copy number variants and differ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dong, Gaochao, Mao, Qixing, Yu, Decai, Zhang, Yi, Qiu, Mantang, Dong, Gaoyue, Chen, Qiang, Xia, Wenjie, Wang, Jie, Xu, Lin, Jiang, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294420/ https://www.ncbi.nlm.nih.gov/pubmed/28169357 http://dx.doi.org/10.1038/srep42060

Ejemplares similares

Predictive Value of Ercc1 and Xpd Polymorphisms for Clinical Outcomes of Patients Receiving Neoadjuvant Therapy: A Prisma-Compliant Meta-Analysis
por: Qixing, Mao, et al.
Publicado: (2015)

Diisopropylamine dichloroacetate enhances radiosensitization in esophageal squamous cell carcinoma by increasing mitochondria-derived reactive oxygen species levels
por: Dong, Gaochao, et al.
Publicado: (2016)

CAG repeat polymorphisms in the androgen receptor and breast cancer risk in women: a meta-analysis of 17 studies
por: Mao, Qixing, et al.
Publicado: (2015)

Integrative analysis of differential genes and identification of a “2‐gene score” associated with survival in esophageal squamous cell carcinoma
por: Wang, Lin, et al.
Publicado: (2018)

Microarray analyses reveal genes related to progression and prognosis of esophageal squamous cell carcinoma
por: Qixing, Mao, et al.
Publicado: (2017)

Effect of lymph node examined count on accurate staging and survival of resected esophageal cancer
por: Xia, Wenjie, et al.
Publicado: (2019)

Glypican-5 suppresses Epithelial-Mesenchymal Transition of the lung adenocarcinoma by competitively binding to Wnt3a
por: Wang, Siwei, et al.
Publicado: (2016)

Aberrant super-enhancer landscape reveals core transcriptional regulatory circuitry in lung adenocarcinoma
por: Zhang, Te, et al.
Publicado: (2020)

Identification and Characterization of Copy Number-Associated Driver Genes in Esophageal Squamous Cell Carcinoma
por: Jiang, Kexin, et al.
Publicado: (2020)

Gut Microbiota Shapes the Efficiency of Cancer Therapy
por: Ma, Weidong, et al.
Publicado: (2019)

CircIMMP2L promotes esophageal squamous cell carcinoma malignant progression via CtBP1 nuclear retention dependent epigenetic modification
por: Liang, Yingkuan, et al.
Publicado: (2021)

Tertiary lymphoid structures favor outcome in resected esophageal squamous cell carcinoma
por: Li, Rutao, et al.
Publicado: (2022)

Clinical and prognostic implications of an immune‐related risk model based on TP53 status in lung adenocarcinoma
por: Song, Xuming, et al.
Publicado: (2021)

RUBIC identifies driver genes by detecting recurrent DNA copy number breaks
por: van Dyk, Ewald, et al.
Publicado: (2016)

PKM2 and cancer: The function of PKM2 beyond glycolysis
por: DONG, GAOCHAO, et al.
Publicado: (2016)

Circular RNA has_circ_0067934 is upregulated in esophageal squamous cell carcinoma and promoted proliferation
por: Xia, Wenjia, et al.
Publicado: (2016)

DNA methylation mediated silencing of microRNA-145 is a potential prognostic marker in patients with lung adenocarcinoma
por: Xia, Wenjie, et al.
Publicado: (2015)

The Long Noncoding RNA LINC00665 Facilitates c-Myc Transcriptional Activity via the miR-195-5p MYCBP Axis to Promote Progression of Lung Adenocarcinoma
por: Wang, Anpeng, et al.
Publicado: (2021)

Pan-cancer driver copy number alterations identified by joint expression/CNA data analysis
por: Wang, Gaojianyong, et al.
Publicado: (2020)

Novel Candidate Key Drivers in the Integrative Network of Genes, MicroRNAs, Methylations, and Copy Number Variations in Squamous Cell Lung Carcinoma
por: Huang, Tao, et al.
Publicado: (2015)

CT-Based Deep Learning Model for Invasiveness Classification and Micropapillary Pattern Prediction Within Lung Adenocarcinoma
por: Ding, Hanlin, et al.
Publicado: (2020)

Circular RNA circCRIM1 inhibits invasion and metastasis in lung adenocarcinoma through the microRNA (miR)‐182/miR‐93‐leukemia inhibitory factor receptor pathway
por: Wang, Lin, et al.
Publicado: (2019)

Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors
por: Ohshima, Keiichi, et al.
Publicado: (2017)

Young age increases risk for lymph node positivity but decreases risk for non-small cell lung cancer death
por: Xia, Wenjie, et al.
Publicado: (2018)

Improvement of survival for non-small cell lung cancer over time
por: Xia, Wenjie, et al.
Publicado: (2017)

An Integrative Analysis to Identify Driver Genes in Esophageal Squamous Cell Carcinoma
por: Sawada, Genta, et al.
Publicado: (2015)

Non-genetic stratification reveals epigenetic heterogeneity and identifies vulnerabilities of glycolysis addiction in lung adenocarcinoma subtype
por: Song, Xuming, et al.
Publicado: (2022)

Identifying the driver miRNAs with somatic copy number alterations driving dysregulated ceRNA networks in cancers
por: Dou, Renjie, et al.
Publicado: (2023)

Integrative Analysis of Transcriptional Regulatory Network and Copy Number Variation in Intrahepatic Cholangiocarcinoma
por: Li, Ling, et al.
Publicado: (2014)

The TWIST1-centered competing endogenous RNA network promotes proliferation, invasion, and migration of lung adenocarcinoma
por: Xia, Wenjie, et al.
Publicado: (2019)

Focal Chromosomal Copy Number Aberrations Identify CMTM8 and GPR177 as New Candidate Driver Genes in Osteosarcoma
por: Both, Joeri, et al.
Publicado: (2014)

Integration of DNA Copy Number Alterations and Transcriptional Expression Analysis in Human Gastric Cancer
por: Fan, Biao, et al.
Publicado: (2012)

Integration of transcript expression, copy number and LOH analysis of infiltrating ductal carcinoma of the breast
por: Hawthorn, Lesleyann, et al.
Publicado: (2010)

Gliosarcoma: The Distinct Genomic Alterations Identified by Comprehensive Analysis of Copy Number Variations
por: Cheng, Chuan-dong, et al.
Publicado: (2022)

Epidermal Growth Factor (EGFR) copy number aberrations in esophageal and gastro-esophageal junctional carcinoma
por: Dahle-Smith, Åsa, et al.
Publicado: (2015)

A network-based signature to predict the survival of non-smoking lung adenocarcinoma
por: Mao, Qixing, et al.
Publicado: (2018)

circDCUN1D4 suppresses tumor metastasis and glycolysis in lung adenocarcinoma by stabilizing TXNIP expression
por: Liang, Yingkuan, et al.
Publicado: (2020)

Driver Mutations and Single Copy Number Abnormalities Identify Binet Stage A Patients with Chronic Lymphocytic Leukemia with Aggressive Progression
por: Gonzalez-Rodriguez, Ana P., et al.
Publicado: (2020)

Identification of driver copy number alterations in diverse cancer types and application in drug repositioning
por: Zhou, Wenbin, et al.
Publicado: (2017)

Defining Signatures of Arm-Wise Copy Number Change and Their Associated Drivers in Kidney Cancers
por: Benstead-Hume, Graeme, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_76cdir89772jp7p1bv1cjmec9s