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Tumour microenvironment factors shaping the cancer metabolism landscape
Cancer cells exhibit metabolic alterations that distinguish them from healthy tissues and make their metabolic processes susceptible to pharmacological targeting. Although typical cell-autonomous features of cancer metabolism have been emerging, it is increasingly appreciated that extrinsic factors...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294476/ https://www.ncbi.nlm.nih.gov/pubmed/28006817 http://dx.doi.org/10.1038/bjc.2016.412 |
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| author | Anastasiou, Dimitrios |
| author_facet | Anastasiou, Dimitrios |
| author_sort | Anastasiou, Dimitrios |
| collection | PubMed |
| description | Cancer cells exhibit metabolic alterations that distinguish them from healthy tissues and make their metabolic processes susceptible to pharmacological targeting. Although typical cell-autonomous features of cancer metabolism have been emerging, it is increasingly appreciated that extrinsic factors also influence the metabolic properties of tumours. This review highlights evidence from the recent literature to discuss how conditions within the tumour microenvironment shape the metabolic character of tumours. |
| format | Online Article Text |
| id | pubmed-5294476 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | Nature Publishing Group |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-52944762017-02-10 Tumour microenvironment factors shaping the cancer metabolism landscape Anastasiou, Dimitrios Br J Cancer Review Cancer cells exhibit metabolic alterations that distinguish them from healthy tissues and make their metabolic processes susceptible to pharmacological targeting. Although typical cell-autonomous features of cancer metabolism have been emerging, it is increasingly appreciated that extrinsic factors also influence the metabolic properties of tumours. This review highlights evidence from the recent literature to discuss how conditions within the tumour microenvironment shape the metabolic character of tumours. Nature Publishing Group 2017-01-31 2016-12-22 /pmc/articles/PMC5294476/ /pubmed/28006817 http://dx.doi.org/10.1038/bjc.2016.412 Text en Copyright © 2017 The Author(s) https://creativecommons.org/licenses/by-nc-sa/4.0/This work is licensed under the Creative Commons Attribution-Non-Commercial-Share Alike 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/ (https://creativecommons.org/licenses/by-nc-sa/4.0/) |
| spellingShingle | Review Anastasiou, Dimitrios Tumour microenvironment factors shaping the cancer metabolism landscape |
| title | Tumour microenvironment factors shaping the cancer metabolism landscape |
| title_full | Tumour microenvironment factors shaping the cancer metabolism landscape |
| title_fullStr | Tumour microenvironment factors shaping the cancer metabolism landscape |
| title_full_unstemmed | Tumour microenvironment factors shaping the cancer metabolism landscape |
| title_short | Tumour microenvironment factors shaping the cancer metabolism landscape |
| title_sort | tumour microenvironment factors shaping the cancer metabolism landscape |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294476/ https://www.ncbi.nlm.nih.gov/pubmed/28006817 http://dx.doi.org/10.1038/bjc.2016.412 |
| work_keys_str_mv | AT anastasioudimitrios tumourmicroenvironmentfactorsshapingthecancermetabolismlandscape |