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Regulation of anoikis resistance by NADPH oxidase 4 and epidermal growth factor receptor

BACKGROUND: Normal cells are sensitive to anoikis, which is a cell detachment-induced apoptosis. However, cancer cells acquire anoikis resistance that is essential for successful metastasis. This study aimed to demonstrate the function and potential mechanism of NADPH oxidase 4 (NOX4) and EGFR activ...

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Detalles Bibliográficos
Autores principales: Kim, Hyeryeong, Sung, Jee Young, Park, Eun-Kyung, Kho, Seongho, Koo, Kyung Hee, Park, Seog-Yun, Goh, Sung-Ho, Jeon, Yoon Kyung, Oh, Sekyung, Park, Byung-Kiu, Jung, Yong-Keun, Kim, Yong-Nyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294491/
https://www.ncbi.nlm.nih.gov/pubmed/28081539
http://dx.doi.org/10.1038/bjc.2016.440