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Image reconstruction from photon sparse data
We report an algorithm for reconstructing images when the average number of photons recorded per pixel is of order unity, i.e. photon-sparse data. The image optimisation algorithm minimises a cost function incorporating both a Poissonian log-likelihood term based on the deviation of the reconstructe...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294572/ https://www.ncbi.nlm.nih.gov/pubmed/28169363 http://dx.doi.org/10.1038/srep42164 |
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author | Mertens, Lena Sonnleitner, Matthias Leach, Jonathan Agnew, Megan Padgett, Miles J. |
author_facet | Mertens, Lena Sonnleitner, Matthias Leach, Jonathan Agnew, Megan Padgett, Miles J. |
author_sort | Mertens, Lena |
collection | PubMed |
description | We report an algorithm for reconstructing images when the average number of photons recorded per pixel is of order unity, i.e. photon-sparse data. The image optimisation algorithm minimises a cost function incorporating both a Poissonian log-likelihood term based on the deviation of the reconstructed image from the measured data and a regularization-term based upon the sum of the moduli of the second spatial derivatives of the reconstructed image pixel intensities. The balance between these two terms is set by a bootstrapping technique where the target value of the log-likelihood term is deduced from a smoothed version of the original data. When compared to the original data, the processed images exhibit lower residuals with respect to the true object. We use photon-sparse data from two different experimental systems, one system based on a single-photon, avalanche photo-diode array and the other system on a time-gated, intensified camera. However, this same processing technique could most likely be applied to any low photon-number image irrespective of how the data is collected. |
format | Online Article Text |
id | pubmed-5294572 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-52945722017-02-10 Image reconstruction from photon sparse data Mertens, Lena Sonnleitner, Matthias Leach, Jonathan Agnew, Megan Padgett, Miles J. Sci Rep Article We report an algorithm for reconstructing images when the average number of photons recorded per pixel is of order unity, i.e. photon-sparse data. The image optimisation algorithm minimises a cost function incorporating both a Poissonian log-likelihood term based on the deviation of the reconstructed image from the measured data and a regularization-term based upon the sum of the moduli of the second spatial derivatives of the reconstructed image pixel intensities. The balance between these two terms is set by a bootstrapping technique where the target value of the log-likelihood term is deduced from a smoothed version of the original data. When compared to the original data, the processed images exhibit lower residuals with respect to the true object. We use photon-sparse data from two different experimental systems, one system based on a single-photon, avalanche photo-diode array and the other system on a time-gated, intensified camera. However, this same processing technique could most likely be applied to any low photon-number image irrespective of how the data is collected. Nature Publishing Group 2017-02-07 /pmc/articles/PMC5294572/ /pubmed/28169363 http://dx.doi.org/10.1038/srep42164 Text en Copyright © 2017, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Mertens, Lena Sonnleitner, Matthias Leach, Jonathan Agnew, Megan Padgett, Miles J. Image reconstruction from photon sparse data |
title | Image reconstruction from photon sparse data |
title_full | Image reconstruction from photon sparse data |
title_fullStr | Image reconstruction from photon sparse data |
title_full_unstemmed | Image reconstruction from photon sparse data |
title_short | Image reconstruction from photon sparse data |
title_sort | image reconstruction from photon sparse data |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294572/ https://www.ncbi.nlm.nih.gov/pubmed/28169363 http://dx.doi.org/10.1038/srep42164 |
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