Pigment epithelium-derived factor attenuates myocardial fibrosis via inhibiting Endothelial-to-Mesenchymal Transition in rats with acute myocardial infarction

Endothelial mesenchymal transition (EndMT) plays a critical role in the pathogenesis and progression of interstitial and perivascular fibrosis after acute myocardial infarction (AMI). Pigment epithelium-derived factor (PEDF) is shown to be a new therapeutic target owing to its protective role in car...

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Detalles Bibliográficos
Autores principales: Zhang, Hao, Hui, Hongliang, Li, Zhimin, Pan, Jiajun, Jiang, Xia, Wei, Tengteng, Cui, Huazhu, Li, Lei, Yuan, Xulong, Sun, Teng, Liu, Zhiwei, Zhang, Zhongming, Dong, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294634/
https://www.ncbi.nlm.nih.gov/pubmed/28167820
http://dx.doi.org/10.1038/srep41932

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