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Results of a planned interim toxicity analysis with trimodality therapy, including carboplatin AUC = 4, paclitaxel, 5-fluorouracil, amifostine, and radiation for locally advanced esophageal cancer: preliminary analyses and treatment recommendations from the North Central Cancer Treatment Group

PURPOSE: An aggressive trimodality approach from the Minnie Pearl Cancer Research Network [carboplatin AUC = 6, days 1 and 22; 5-fluorouracil 225 mg/m2 continuous infusion, days 1–42, paclitaxel 200 mg/m2, days 1 and 22; 45 Gy] has resulted in remarkable pathologic response rates but notable toxicit...

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Detalles Bibliográficos
Autores principales: Jatoi, Aminah, Martenson, James, Mahoney, Michelle R, Lair, Bradley S, Brindle, Jeffrey S, Nichols, Frank, Caron, Normand, Rowland, Kendrith, Tschetter, Loren, Alberts, Steven
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC529465/
https://www.ncbi.nlm.nih.gov/pubmed/15533252
http://dx.doi.org/10.1186/1477-7800-1-9