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Community effectiveness of chloroquine and traditional remedies in the treatment of young children with falciparum malaria in rural Burkina Faso

BACKGROUND: There is little information on the effectiveness of modern compared to traditional malaria treatment from the rural areas of Africa. METHODS: Follow-up of 402 episodes of clinical malaria among pre-school children in Nouna Health District, northwestern Burkina Faso. The exposure of inter...

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Detalles Bibliográficos
Autores principales: Mueller, Olaf, Razum, Oliver, Traore, Corneille, Kouyate, Bocar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC529468/
https://www.ncbi.nlm.nih.gov/pubmed/15496225
http://dx.doi.org/10.1186/1475-2875-3-36
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author Mueller, Olaf
Razum, Oliver
Traore, Corneille
Kouyate, Bocar
author_facet Mueller, Olaf
Razum, Oliver
Traore, Corneille
Kouyate, Bocar
author_sort Mueller, Olaf
collection PubMed
description BACKGROUND: There is little information on the effectiveness of modern compared to traditional malaria treatment from the rural areas of Africa. METHODS: Follow-up of 402 episodes of clinical malaria among pre-school children in Nouna Health District, northwestern Burkina Faso. The exposure of interest was the type of treatment (chloroquine versus traditional); the outcome was clinical response to treatment. RESULTS: Out of the 402 observed malaria episodes, 87% were treated with chloroquine and 13% with traditional remedies. Overall, community effectiveness was 67% with chloroquine and 54% with traditional treatment. Chloroquine effectiveness was associated with age and ethnicity. An additional interview survey demonstrated wide variations in the dosages of chloroquine given to young children in this community. CONCLUSIONS: The effectiveness of chloroquine, when used within the community, was significantly lower in this study than its known efficacy in the study area. This concerns, in particular, the very young children. These findings demonstrate the need for better education of parents about correct dosage of first-line malaria drugs, and for particular attention in the treatment of very young children.
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spelling pubmed-5294682004-11-21 Community effectiveness of chloroquine and traditional remedies in the treatment of young children with falciparum malaria in rural Burkina Faso Mueller, Olaf Razum, Oliver Traore, Corneille Kouyate, Bocar Malar J Research BACKGROUND: There is little information on the effectiveness of modern compared to traditional malaria treatment from the rural areas of Africa. METHODS: Follow-up of 402 episodes of clinical malaria among pre-school children in Nouna Health District, northwestern Burkina Faso. The exposure of interest was the type of treatment (chloroquine versus traditional); the outcome was clinical response to treatment. RESULTS: Out of the 402 observed malaria episodes, 87% were treated with chloroquine and 13% with traditional remedies. Overall, community effectiveness was 67% with chloroquine and 54% with traditional treatment. Chloroquine effectiveness was associated with age and ethnicity. An additional interview survey demonstrated wide variations in the dosages of chloroquine given to young children in this community. CONCLUSIONS: The effectiveness of chloroquine, when used within the community, was significantly lower in this study than its known efficacy in the study area. This concerns, in particular, the very young children. These findings demonstrate the need for better education of parents about correct dosage of first-line malaria drugs, and for particular attention in the treatment of very young children. BioMed Central 2004-10-20 /pmc/articles/PMC529468/ /pubmed/15496225 http://dx.doi.org/10.1186/1475-2875-3-36 Text en Copyright © 2004 Mueller et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Mueller, Olaf
Razum, Oliver
Traore, Corneille
Kouyate, Bocar
Community effectiveness of chloroquine and traditional remedies in the treatment of young children with falciparum malaria in rural Burkina Faso
title Community effectiveness of chloroquine and traditional remedies in the treatment of young children with falciparum malaria in rural Burkina Faso
title_full Community effectiveness of chloroquine and traditional remedies in the treatment of young children with falciparum malaria in rural Burkina Faso
title_fullStr Community effectiveness of chloroquine and traditional remedies in the treatment of young children with falciparum malaria in rural Burkina Faso
title_full_unstemmed Community effectiveness of chloroquine and traditional remedies in the treatment of young children with falciparum malaria in rural Burkina Faso
title_short Community effectiveness of chloroquine and traditional remedies in the treatment of young children with falciparum malaria in rural Burkina Faso
title_sort community effectiveness of chloroquine and traditional remedies in the treatment of young children with falciparum malaria in rural burkina faso
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC529468/
https://www.ncbi.nlm.nih.gov/pubmed/15496225
http://dx.doi.org/10.1186/1475-2875-3-36
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