Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis

BACKGROUND: Central nervous system tuberculosis (CNS-TB) may be fatal even with treatment. Neutrophils are the key mediators of TB immunopathology, and raised CSF matrix metalloproteinase-9 (MMP-9) which correlates to neutrophil count in CNS-TB is associated with neurological deficit and death. The...

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Detalles Bibliográficos
Autores principales: Ong, Catherine W. M., Pabisiak, Przemyslaw J., Brilha, Sara, Singh, Poonam, Roncaroli, Federico, Elkington, Paul T., Friedland, Jon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294728/
https://www.ncbi.nlm.nih.gov/pubmed/28173836
http://dx.doi.org/10.1186/s12974-017-0801-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294728/
https://www.ncbi.nlm.nih.gov/pubmed/28173836
http://dx.doi.org/10.1186/s12974-017-0801-1

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