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Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis
BACKGROUND: Central nervous system tuberculosis (CNS-TB) may be fatal even with treatment. Neutrophils are the key mediators of TB immunopathology, and raised CSF matrix metalloproteinase-9 (MMP-9) which correlates to neutrophil count in CNS-TB is associated with neurological deficit and death. The...
Autores principales: | Ong, Catherine W. M., Pabisiak, Przemyslaw J., Brilha, Sara, Singh, Poonam, Roncaroli, Federico, Elkington, Paul T., Friedland, Jon S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294728/ https://www.ncbi.nlm.nih.gov/pubmed/28173836 http://dx.doi.org/10.1186/s12974-017-0801-1 |
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