Early Effect of Amyloid β-Peptide on Hippocampal and Serum Metabolism in Rats Studied by an Integrated Method of NMR-Based Metabolomics and ANOVA-Simultaneous Component Analysis

Amyloid β (Aβ) deposition has been implicated in the pathogenesis of Alzheimer's disease. However, the early effect of Aβ deposition on metabolism remains unclear. In the present study, thus, we explored the metabolic changes in the hippocampus and serum during first 2 weeks of Aβ (25–35) injec...

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Detalles Bibliográficos
Autores principales: Du, Yao, Zheng, Hong, Xia, Huanhuan, Zhao, Liangcai, Hu, Wenyi, Bai, Guanghui, Yan, Zhihan, Gao, Hongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294748/
https://www.ncbi.nlm.nih.gov/pubmed/28243597
http://dx.doi.org/10.1155/2017/3262495

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