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Noncanonical function of DGCR8 controls mESC exit from pluripotency

Mouse embryonic stem cells (mESCs) deficient for DGCR8, a key component of the microprocessor complex, present strong differentiation defects. However, the exact reasons impairing their commitment remain elusive. The analysis of newly generated mutant mESCs revealed that DGCR8 is essential for the e...

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Detalles Bibliográficos
Autores principales:	Cirera-Salinas, Daniel, Yu, Jian, Bodak, Maxime, Ngondo, Richard P., Herbert, Kristina M., Ciaudo, Constance
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294780/ https://www.ncbi.nlm.nih.gov/pubmed/28100686 http://dx.doi.org/10.1083/jcb.201606073

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