Cargando…

A STRIPAK complex mediates axonal transport of autophagosomes and dense core vesicles through PP2A regulation

Autophagy plays an essential role in the cellular homeostasis of neurons, facilitating the clearance of cellular debris. This clearance process is orchestrated through the assembly, transport, and fusion of autophagosomes with lysosomes for degradation. The motor protein dynein drives autophagosome...

Descripción completa

Detalles Bibliográficos
Autores principales: Neisch, Amanda L., Neufeld, Thomas P., Hays, Thomas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294782/
https://www.ncbi.nlm.nih.gov/pubmed/28100687
http://dx.doi.org/10.1083/jcb.201606082