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A STRIPAK complex mediates axonal transport of autophagosomes and dense core vesicles through PP2A regulation
Autophagy plays an essential role in the cellular homeostasis of neurons, facilitating the clearance of cellular debris. This clearance process is orchestrated through the assembly, transport, and fusion of autophagosomes with lysosomes for degradation. The motor protein dynein drives autophagosome...
Autores principales: | Neisch, Amanda L., Neufeld, Thomas P., Hays, Thomas S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294782/ https://www.ncbi.nlm.nih.gov/pubmed/28100687 http://dx.doi.org/10.1083/jcb.201606082 |
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