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Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells

Glycolytic enzymes are known to play pivotal roles in cancer cell survival, yet their molecular mechanisms remain poorly understood. Phosphoglycerate mutase 1 (PGAM1) is an important glycolytic enzyme that coordinates glycolysis, pentose phosphate pathway, and serine biosynthesis in cancer cells. He...

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Detalles Bibliográficos
Autores principales:	Qu, Jia, Sun, Wenyi, Zhong, Jie, Lv, Hao, Zhu, Mingrui, Xu, Jun, Jin, Nan, Xie, Zuoquan, Tan, Minjia, Lin, Shu-Hai, Geng, Meiyu, Ding, Jian, Huang, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294784/ https://www.ncbi.nlm.nih.gov/pubmed/28122957 http://dx.doi.org/10.1083/jcb.201607008

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