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Localization of mTORC2 activity inside cells

Activation of protein kinase Akt via its direct phosphorylation by mammalian target of rapamycin (mTOR) complex 2 (mTORC2) couples extracellular growth and survival cues with pathways controlling cell growth and proliferation, yet how growth factors target the activity of mTORC2 toward Akt is unknow...

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Detalles Bibliográficos
Autores principales:	Ebner, Michael, Sinkovics, Benjamin, Szczygieł, Magdalena, Ribeiro, Daniela Wolfschoon, Yudushkin, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294791/ https://www.ncbi.nlm.nih.gov/pubmed/28143890 http://dx.doi.org/10.1083/jcb.201610060

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