Integration of VDR genome wide binding and GWAS genetic variation data reveals co-occurrence of VDR and NF-κB binding that is linked to immune phenotypes

BACKGROUND: The nuclear hormone receptor superfamily acts as a genomic sensor of diverse signals. Their actions are often intertwined with other transcription factors. Nuclear hormone receptors are targets for many therapeutic drugs, and include the vitamin D receptor (VDR). VDR signaling is pleotro...

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Detalles Bibliográficos
Autores principales: Singh, Prashant K., van den Berg, Patrick R., Long, Mark D., Vreugdenhil, Angie, Grieshober, Laurie, Ochs-Balcom, Heather M., Wang, Jianmin, Delcambre, Sylvie, Heikkinen, Sami, Carlberg, Carsten, Campbell, Moray J., Sucheston-Campbell, Lara E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294817/
https://www.ncbi.nlm.nih.gov/pubmed/28166722
http://dx.doi.org/10.1186/s12864-017-3481-4

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