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Dissection of SAP-dependent and SAP-independent SLAM family signaling in NKT cell development and humoral immunity
Signaling lymphocytic activation molecule (SLAM)–associated protein (SAP) mutations in X-linked lymphoproliferative disease (XLP) lead to defective NKT cell development and impaired humoral immunity. Because of the redundancy of SLAM family receptors (SFRs) and the complexity of SAP actions, how SFR...
Autores principales: | Chen, Shasha, Cai, Chenxu, Li, Zehua, Liu, Guangao, Wang, Yuande, Blonska, Marzenna, Li, Dan, Du, Juan, Lin, Xin, Yang, Meixiang, Dong, Zhongjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294859/ https://www.ncbi.nlm.nih.gov/pubmed/28049627 http://dx.doi.org/10.1084/jem.20161312 |
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