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Dissection of SAP-dependent and SAP-independent SLAM family signaling in NKT cell development and humoral immunity

Signaling lymphocytic activation molecule (SLAM)–associated protein (SAP) mutations in X-linked lymphoproliferative disease (XLP) lead to defective NKT cell development and impaired humoral immunity. Because of the redundancy of SLAM family receptors (SFRs) and the complexity of SAP actions, how SFR...

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Detalles Bibliográficos
Autores principales: Chen, Shasha, Cai, Chenxu, Li, Zehua, Liu, Guangao, Wang, Yuande, Blonska, Marzenna, Li, Dan, Du, Juan, Lin, Xin, Yang, Meixiang, Dong, Zhongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294859/
https://www.ncbi.nlm.nih.gov/pubmed/28049627
http://dx.doi.org/10.1084/jem.20161312

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