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Induction of complex immune responses and strong protection against retrovirus challenge by adenovirus-based immunization depends on the order of vaccine delivery
BACKGROUND: In the Friend retrovirus mouse model we developed potent adenovirus-based vaccines that were designed to induce either strong Friend virus GagL(85–93)-specific CD8(+) T cell or antibody responses, respectively. To optimize the immunization outcome we evaluated vaccination strategies usin...
Autores principales: | Kaulfuß, Meike, Wensing, Ina, Windmann, Sonja, Hrycak, Camilla Patrizia, Bayer, Wibke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294899/ https://www.ncbi.nlm.nih.gov/pubmed/28166802 http://dx.doi.org/10.1186/s12977-017-0336-7 |
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