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Evaluation of logistic regression models and effect of covariates for case–control study in RNA-Seq analysis

BACKGROUND: Next generation sequencing provides a count of RNA molecules in the form of short reads, yielding discrete, often highly non-normally distributed gene expression measurements. Although Negative Binomial (NB) regression has been generally accepted in the analysis of RNA sequencing (RNA-Se...

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Detalles Bibliográficos
Autores principales: Choi, Seung Hoan, Labadorf, Adam T., Myers, Richard H., Lunetta, Kathryn L., Dupuis, Josée, DeStefano, Anita L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294900/
https://www.ncbi.nlm.nih.gov/pubmed/28166718
http://dx.doi.org/10.1186/s12859-017-1498-y