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Evaluation of logistic regression models and effect of covariates for case–control study in RNA-Seq analysis
BACKGROUND: Next generation sequencing provides a count of RNA molecules in the form of short reads, yielding discrete, often highly non-normally distributed gene expression measurements. Although Negative Binomial (NB) regression has been generally accepted in the analysis of RNA sequencing (RNA-Se...
Autores principales: | Choi, Seung Hoan, Labadorf, Adam T., Myers, Richard H., Lunetta, Kathryn L., Dupuis, Josée, DeStefano, Anita L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294900/ https://www.ncbi.nlm.nih.gov/pubmed/28166718 http://dx.doi.org/10.1186/s12859-017-1498-y |
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