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The TGF-β/Smad4 Signaling Pathway in Pancreatic Carcinogenesis and Its Clinical Significance

Pancreatic ductal adenocarcinoma (PDAC) is one of the most fatal human cancers due to its complicated genomic instability. PDAC frequently presents at an advanced stage with extensive metastasis, which portends a poor prognosis. The known risk factors associated with PDAC include advanced age, smoki...

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Detalles Bibliográficos
Autores principales: Ahmed, Sunjida, Bradshaw, Azore-Dee, Gera, Shweta, Dewan, M. Zahidunnabi, Xu, Ruliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294958/
https://www.ncbi.nlm.nih.gov/pubmed/28067794
http://dx.doi.org/10.3390/jcm6010005

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