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Envelope Protein Mutations L107F and E138K Are Important for Neurovirulence Attenuation for Japanese Encephalitis Virus SA14-14-2 Strain

The attenuated Japanese encephalitis virus (JEV) strain SA14-14-2 has been successfully utilized to prevent JEV infection; however, the attenuation determinants have not been fully elucidated. The envelope (E) protein of the attenuated JEV SA14-14-2 strain differs from that of the virulent parental...

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Detalles Bibliográficos
Autores principales: Yang, Jian, Yang, Huiqiang, Li, Zhushi, Wang, Wei, Lin, Hua, Liu, Lina, Ni, Qianzhi, Liu, Xinyu, Zeng, Xianwu, Wu, Yonglin, Li, Yuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294989/
https://www.ncbi.nlm.nih.gov/pubmed/28117725
http://dx.doi.org/10.3390/v9010020