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Envelope Protein Mutations L107F and E138K Are Important for Neurovirulence Attenuation for Japanese Encephalitis Virus SA14-14-2 Strain
The attenuated Japanese encephalitis virus (JEV) strain SA14-14-2 has been successfully utilized to prevent JEV infection; however, the attenuation determinants have not been fully elucidated. The envelope (E) protein of the attenuated JEV SA14-14-2 strain differs from that of the virulent parental...
Autores principales: | Yang, Jian, Yang, Huiqiang, Li, Zhushi, Wang, Wei, Lin, Hua, Liu, Lina, Ni, Qianzhi, Liu, Xinyu, Zeng, Xianwu, Wu, Yonglin, Li, Yuhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294989/ https://www.ncbi.nlm.nih.gov/pubmed/28117725 http://dx.doi.org/10.3390/v9010020 |
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