Nuclear Import of Hepatitis B Virus Capsids and Genome

Hepatitis B virus (HBV) is an enveloped pararetrovirus with a DNA genome, which is found in an up to 36 nm-measuring capsid. Replication of the genome occurs via an RNA intermediate, which is synthesized in the nucleus. The virus must have thus ways of transporting its DNA genome into this compartme...

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Detalles Bibliográficos
Autores principales: Gallucci, Lara, Kann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294990/
https://www.ncbi.nlm.nih.gov/pubmed/28117723
http://dx.doi.org/10.3390/v9010021
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author Gallucci, Lara
Kann, Michael
author_facet Gallucci, Lara
Kann, Michael
author_sort Gallucci, Lara
collection PubMed
description Hepatitis B virus (HBV) is an enveloped pararetrovirus with a DNA genome, which is found in an up to 36 nm-measuring capsid. Replication of the genome occurs via an RNA intermediate, which is synthesized in the nucleus. The virus must have thus ways of transporting its DNA genome into this compartment. This review summarizes the data on hepatitis B virus genome transport and correlates the finding to those from other viruses.
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spelling pubmed-52949902017-02-10 Nuclear Import of Hepatitis B Virus Capsids and Genome Gallucci, Lara Kann, Michael Viruses Review Hepatitis B virus (HBV) is an enveloped pararetrovirus with a DNA genome, which is found in an up to 36 nm-measuring capsid. Replication of the genome occurs via an RNA intermediate, which is synthesized in the nucleus. The virus must have thus ways of transporting its DNA genome into this compartment. This review summarizes the data on hepatitis B virus genome transport and correlates the finding to those from other viruses. MDPI 2017-01-21 /pmc/articles/PMC5294990/ /pubmed/28117723 http://dx.doi.org/10.3390/v9010021 Text en © 2017 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Gallucci, Lara
Kann, Michael
Nuclear Import of Hepatitis B Virus Capsids and Genome
title Nuclear Import of Hepatitis B Virus Capsids and Genome
title_full Nuclear Import of Hepatitis B Virus Capsids and Genome
title_fullStr Nuclear Import of Hepatitis B Virus Capsids and Genome
title_full_unstemmed Nuclear Import of Hepatitis B Virus Capsids and Genome
title_short Nuclear Import of Hepatitis B Virus Capsids and Genome
title_sort nuclear import of hepatitis b virus capsids and genome
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294990/
https://www.ncbi.nlm.nih.gov/pubmed/28117723
http://dx.doi.org/10.3390/v9010021
work_keys_str_mv AT galluccilara nuclearimportofhepatitisbviruscapsidsandgenome
AT kannmichael nuclearimportofhepatitisbviruscapsidsandgenome

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