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Regulation and Function of Cdt1; A Key Factor in Cell Proliferation and Genome Stability

Successful cell proliferation requires efficient and precise genome duplication followed by accurate chromosome segregation. The Cdc10-dependent transcript 1 protein (Cdt1) is required for the first step in DNA replication, and in human cells Cdt1 is also required during mitosis. Tight cell cycle co...

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Detalles Bibliográficos
Autores principales: Pozo, Pedro N., Cook, Jeanette Gowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294997/
https://www.ncbi.nlm.nih.gov/pubmed/28025526
http://dx.doi.org/10.3390/genes8010002

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