Maintenance of Genome Integrity: How Mammalian Cells Orchestrate Genome Duplication by Coordinating Replicative and Specialized DNA Polymerases

Precise duplication of the human genome is challenging due to both its size and sequence complexity. DNA polymerase errors made during replication, repair or recombination are central to creating mutations that drive cancer and aging. Here, we address the regulation of human DNA polymerases, specifi...

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Detalles Bibliográficos
Autores principales: Barnes, Ryan, Eckert, Kristin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295014/
https://www.ncbi.nlm.nih.gov/pubmed/28067843
http://dx.doi.org/10.3390/genes8010019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295014/
https://www.ncbi.nlm.nih.gov/pubmed/28067843
http://dx.doi.org/10.3390/genes8010019

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