Sulfolobus acidocaldarius UDG Can Remove dU from the RNA Backbone: Insight into the Specific Recognition of Uracil Linked with Deoxyribose

Sulfolobus acidocaldarius encodes family 4 and 5 uracil-DNA glycosylase (UDG). Two recombinant S. acidocaldarius UDGs (SacUDG) were prepared and biochemically characterized using oligonucleotides carrying a deaminated base. Both SacUDGs can remove deoxyuracil (dU) base from both double-stranded DNA...

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Detalles Bibliográficos
Autores principales: Yi, Gang-Shun, Wang, Wei-Wei, Cao, Wei-Guo, Wang, Feng-Ping, Liu, Xi-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295032/
https://www.ncbi.nlm.nih.gov/pubmed/28106786
http://dx.doi.org/10.3390/genes8010038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295032/
https://www.ncbi.nlm.nih.gov/pubmed/28106786
http://dx.doi.org/10.3390/genes8010038

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