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Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor Heterogeneity
The ability of all organisms to copy their genetic information via DNA replication is a prerequisite for cell division and a biological imperative of life. In multicellular organisms, however, mutations arising from DNA replication errors in the germline and somatic cells are the basis of genetic di...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295039/ https://www.ncbi.nlm.nih.gov/pubmed/28117753 http://dx.doi.org/10.3390/genes8010046 |