Cargando…

Dendritic Cell Targeting Effectively Boosts T Cell Responses Elicited by an HIV Multiepitope DNA Vaccine

Despite several efforts in the last decades, an efficacious HIV-1 vaccine is still not available. Different approaches have been evaluated, such as recombinant proteins, viral vectors, DNA vaccines, and, most recently, dendritic cell (DC) targeting. This strategy is based on DC features that place t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Apostólico, Juliana de Souza, Lunardelli, Victória Alves Santos, Yamamoto, Marcio Massao, Souza, Higo Fernando Santos, Cunha-Neto, Edecio, Boscardin, Silvia Beatriz, Rosa, Daniela Santoro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295143/ https://www.ncbi.nlm.nih.gov/pubmed/28223987 http://dx.doi.org/10.3389/fimmu.2017.00101

Ejemplares similares

Poly(I:C) Potentiates T Cell Immunity to a Dendritic Cell Targeted HIV-Multiepitope Vaccine
por: Apostólico, Juliana de Souza, et al.
Publicado: (2019)

HIV Envelope Trimer Specific Immune Response Is Influenced by Different Adjuvant Formulations and Heterologous Prime-Boost
por: Apostólico, Juliana de Souza, et al.
Publicado: (2016)

Adjuvants: Classification, Modus Operandi, and Licensing
por: Apostólico, Juliana de Souza, et al.
Publicado: (2016)

ZIKV-envelope proteins induce specific humoral and cellular immunity in distinct mice strains
por: Lunardelli, Victória Alves Santos, et al.
Publicado: (2022)

Diagnostic and vaccine potential of Zika virus envelope protein (E) derivates produced in bacterial and insect cells
por: Lunardelli, Victória Alves Santos, et al.
Publicado: (2023)

Prime-boost with Chikungunya virus E2 envelope protein combined with Poly (I:C) induces specific humoral and cellular immune responses
por: Amaral, Marcelo Pires, et al.
Publicado: (2021)

Dendritic Cell Targeting Using a DNA Vaccine Induces Specific Antibodies and CD4(+) T Cells to the Dengue Virus Envelope Protein Domain III
por: Zaneti, Arthur Baruel, et al.
Publicado: (2019)

Time-dependent contraction of the SARS-CoV-2–specific T-cell responses in convalescent individuals
por: Fernandes, Edgar Ruz, et al.
Publicado: (2022)

STAT3 signaling modulates the immune response induced after antigen targeting to conventional type 1 dendritic cells through the DEC205 receptor
por: Sulczewski, Fernando Bandeira, et al.
Publicado: (2022)

STAT6 signaling pathway controls germinal center responses promoted after antigen targeting to conventional type 2 dendritic cells
por: Sulczewski, Fernando Bandeira, et al.
Publicado: (2021)

Robust specific RBD responses and neutralizing antibodies after ChAdOx1 nCoV-19 and CoronaVac vaccination in SARS-CoV-2– seropositive individuals
por: Fernandes, Edgar Ruz, et al.
Publicado: (2023)

A Recombinant Multiepitope Protein for Hepatitis B Diagnosis
por: de Souza, Marilen Queiroz, et al.
Publicado: (2013)

Propionibacterium acnes Enhances the Immunogenicity of HIVBr18 Human Immunodeficiency Virus-1 Vaccine
por: Teixeira, Daniela, et al.
Publicado: (2018)

CpG Oligodeoxinucleotides and Flagellin Modulate the Immune Response to Antigens Targeted to CD8α(+) and CD8α(−) Conventional Dendritic Cell Subsets
por: Antonialli, Renan, et al.
Publicado: (2017)

In silico construction of a multiepitope Zika virus vaccine using immunoinformatics tools
por: Antonelli, Ana Clara Barbosa, et al.
Publicado: (2022)

A Novel Structurally Stable Multiepitope Protein for Detection of HCV
por: Galdino, Alexsandro S., et al.
Publicado: (2016)

Dendritic Cells in Tolerance and Immunity against Pathogens
por: Boscardin, Silvia Beatriz, et al.
Publicado: (2016)

Editorial: Harnessing the Participation of Dendritic Cells in Immunity and Tolerance
por: Boscardin, Silvia Beatriz, et al.
Publicado: (2020)

Multiepitope supramolecular peptide nanofibers eliciting coordinated humoral and cellular antitumor immune responses
por: Wu, Yaoying, et al.
Publicado: (2022)

Intradermal Delivery of Dendritic Cell-Targeting Chimeric mAbs Genetically Fused to Type 2 Dengue Virus Nonstructural Protein 1
por: Pereira, Lennon Ramos, et al.
Publicado: (2020)

A DNA Vaccine Encoding Multiple HIV CD4 Epitopes Elicits Vigorous Polyfunctional, Long-Lived CD4(+) and CD8(+) T Cell Responses
por: Rosa, Daniela Santoro, et al.
Publicado: (2011)

Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses
por: Boscardin, Silvia B., et al.
Publicado: (2006)

Potent HIV-1-Specific CD8 T Cell Responses Induced in Mice after Priming with a Multiepitopic DNA-TMEP and Boosting with the HIV Vaccine MVA-B
por: Perdiguero, Beatriz, et al.
Publicado: (2018)

Broad and Cross-Clade CD4(+) T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides
por: Almeida, Rafael Ribeiro, et al.
Publicado: (2012)

A Heterologous Multiepitope DNA Prime/Recombinant Protein Boost Immunisation Strategy for the Development of an Antiserum against Micrurus corallinus (Coral Snake) Venom
por: Ramos, Henrique Roman, et al.
Publicado: (2016)

P02-12. Bupivacaine, a local anaesthetic, enhances immunogenicity of a multiepitopic DNA vaccine containing HIV promiscuous CD4 T cell epitopes
por: Rosa, DS, et al.
Publicado: (2009)

Sleep Disturbance during Infection Compromises Tfh Differentiation and Impacts Host Immunity
por: Fernandes, Edgar Ruz, et al.
Publicado: (2020)

Development and evaluation of an indirect ELISA using a multiepitope antigen for the diagnosis of intestinal schistosomiasis
por: Lopes, Karine Ferreira, et al.
Publicado: (2023)

A Chikungunya Virus Multiepitope Recombinant Protein Expressed from the Binary System Insect Cell/Recombinant Baculovirus Is Useful for Laboratorial Diagnosis of Chikungunya
por: da Silva, Leonardo Assis, et al.
Publicado: (2022)

Proof of Concept of a Novel Multiepitope Recombinant Protein for the Serodiagnosis of Patients with Chagas Disease
por: Machado, Juliana Martins, et al.
Publicado: (2023)

Co-administration of plasmid-encoded granulocyte-macrophage colony-stimulating factor increases human immunodeficiency virus-1 DNA vaccine-induced polyfunctional CD4(+) T-cell responses
por: Santana, Vinicius Canato, et al.
Publicado: (2015)

Immunoinformatic-based design of immune-boosting multiepitope subunit vaccines against monkeypox virus and validation through molecular dynamics and immune simulation
por: Suleman, Muhammad, et al.
Publicado: (2022)

Current Update on Rotavirus in-Silico Multiepitope Vaccine Design
por: Kuri, Pooja R., et al.
Publicado: (2022)

rMELEISH: A Novel Recombinant Multiepitope-Based Protein Applied to the Serodiagnosis of Both Canine and Human Visceral Leishmaniasis
por: Dias, Daniel Silva, et al.
Publicado: (2023)

Multiepitope Subunit Peptide-Based Nanovaccine against Porcine Circovirus Type 2 (PCV2) Elicited High Antibody Titers in Vaccinated Mice
por: Duong, Viet Tram, et al.
Publicado: (2023)

Induction of Broad and Polyfunctional HIV-1-Specific T Cell Responses by the Multiepitopic Protein TMEP-B Vectored by MVA Virus
por: Perdiguero, Beatriz, et al.
Publicado: (2019)

Multiple-Allele MHC Class II Epitope Engineering by a Molecular Dynamics-Based Evolution Protocol
por: Ochoa, Rodrigo, et al.
Publicado: (2022)

Bioinformatics and Multiepitope DNA Immunization to Design Rational Snake Antivenom
por: Wagstaff, Simon C, et al.
Publicado: (2006)

Vaccinomics to Design a Multiepitope Vaccine against Legionella pneumophila
por: Umar, Ahitsham, et al.
Publicado: (2022)

Searches for narrow resonances decaying to pairs of boosted HH bosons
por: De Souza Santos, Angelo
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_s8vqppd224ubfi4et4v0avh38t