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Structure-Based Design and Synthesis of a New Phenylboronic-Modified Affinity Medium for Metalloprotease Purification
Metalloproteases are emerging as useful agents in the treatment of many diseases including arthritis, cancer, cardiovascular diseases, and fibrosis. Studies that could shed light on the metalloprotease pharmaceutical applications require the pure enzyme. Here, we reported the structure-based design...
Autores principales: | Li, Shangyong, Wang, Linna, Xu, Ximing, Lin, Shengxiang, Wang, Yuejun, Hao, Jianhua, Sun, Mi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295225/ https://www.ncbi.nlm.nih.gov/pubmed/28036010 http://dx.doi.org/10.3390/md15010005 |
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