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Disability Weights for Chronic Mercury Intoxication Resulting from Gold Mining Activities: Results from an Online Pairwise Comparisons Survey

In artisanal small-scale gold mining, mercury is used for gold-extraction, putting miners and nearby residents at risk of chronic metallic mercury vapor intoxication (CMMVI). Burden of disease (BoD) analyses allow the estimation of the public health relevance of CMMVI, but until now there have been...

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Autores principales: Steckling, Nadine, Devleesschauwer, Brecht, Winkelnkemper, Julia, Fischer, Florian, Ericson, Bret, Krämer, Alexander, Hornberg, Claudia, Fuller, Richard, Plass, Dietrich, Bose-O’Reilly, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295308/
https://www.ncbi.nlm.nih.gov/pubmed/28075395
http://dx.doi.org/10.3390/ijerph14010057
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author Steckling, Nadine
Devleesschauwer, Brecht
Winkelnkemper, Julia
Fischer, Florian
Ericson, Bret
Krämer, Alexander
Hornberg, Claudia
Fuller, Richard
Plass, Dietrich
Bose-O’Reilly, Stephan
author_facet Steckling, Nadine
Devleesschauwer, Brecht
Winkelnkemper, Julia
Fischer, Florian
Ericson, Bret
Krämer, Alexander
Hornberg, Claudia
Fuller, Richard
Plass, Dietrich
Bose-O’Reilly, Stephan
author_sort Steckling, Nadine
collection PubMed
description In artisanal small-scale gold mining, mercury is used for gold-extraction, putting miners and nearby residents at risk of chronic metallic mercury vapor intoxication (CMMVI). Burden of disease (BoD) analyses allow the estimation of the public health relevance of CMMVI, but until now there have been no specific CMMVI disability weights (DWs). The objective is to derive DWs for moderate and severe CMMVI. Disease-specific and generic health state descriptions of 18 diseases were used in a pairwise comparison survey. Mercury and BoD experts were invited to participate in an online survey. Data were analyzed using probit regression. Local regression was used to make the DWs comparable to the Global Burden of Disease (GBD) study. Alternative survey (visual analogue scale) and data analyses approaches (linear interpolation) were evaluated in scenario analyses. A total of 105 participants completed the questionnaire. DWs for moderate and severe CMMVI were 0.368 (0.261–0.484) and 0.588 (0.193–0.907), respectively. Scenario analyses resulted in higher mean values. The results are limited by the sample size, group of interviewees, questionnaire extent, and lack of generally accepted health state descriptions. DWs were derived to improve the data basis of mercury-related BoD estimates, providing useful information for policy-making. Integration of the results into the GBD DWs enhances comparability.
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spelling pubmed-52953082017-02-07 Disability Weights for Chronic Mercury Intoxication Resulting from Gold Mining Activities: Results from an Online Pairwise Comparisons Survey Steckling, Nadine Devleesschauwer, Brecht Winkelnkemper, Julia Fischer, Florian Ericson, Bret Krämer, Alexander Hornberg, Claudia Fuller, Richard Plass, Dietrich Bose-O’Reilly, Stephan Int J Environ Res Public Health Article In artisanal small-scale gold mining, mercury is used for gold-extraction, putting miners and nearby residents at risk of chronic metallic mercury vapor intoxication (CMMVI). Burden of disease (BoD) analyses allow the estimation of the public health relevance of CMMVI, but until now there have been no specific CMMVI disability weights (DWs). The objective is to derive DWs for moderate and severe CMMVI. Disease-specific and generic health state descriptions of 18 diseases were used in a pairwise comparison survey. Mercury and BoD experts were invited to participate in an online survey. Data were analyzed using probit regression. Local regression was used to make the DWs comparable to the Global Burden of Disease (GBD) study. Alternative survey (visual analogue scale) and data analyses approaches (linear interpolation) were evaluated in scenario analyses. A total of 105 participants completed the questionnaire. DWs for moderate and severe CMMVI were 0.368 (0.261–0.484) and 0.588 (0.193–0.907), respectively. Scenario analyses resulted in higher mean values. The results are limited by the sample size, group of interviewees, questionnaire extent, and lack of generally accepted health state descriptions. DWs were derived to improve the data basis of mercury-related BoD estimates, providing useful information for policy-making. Integration of the results into the GBD DWs enhances comparability. MDPI 2017-01-10 2017-01 /pmc/articles/PMC5295308/ /pubmed/28075395 http://dx.doi.org/10.3390/ijerph14010057 Text en © 2017 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Steckling, Nadine
Devleesschauwer, Brecht
Winkelnkemper, Julia
Fischer, Florian
Ericson, Bret
Krämer, Alexander
Hornberg, Claudia
Fuller, Richard
Plass, Dietrich
Bose-O’Reilly, Stephan
Disability Weights for Chronic Mercury Intoxication Resulting from Gold Mining Activities: Results from an Online Pairwise Comparisons Survey
title Disability Weights for Chronic Mercury Intoxication Resulting from Gold Mining Activities: Results from an Online Pairwise Comparisons Survey
title_full Disability Weights for Chronic Mercury Intoxication Resulting from Gold Mining Activities: Results from an Online Pairwise Comparisons Survey
title_fullStr Disability Weights for Chronic Mercury Intoxication Resulting from Gold Mining Activities: Results from an Online Pairwise Comparisons Survey
title_full_unstemmed Disability Weights for Chronic Mercury Intoxication Resulting from Gold Mining Activities: Results from an Online Pairwise Comparisons Survey
title_short Disability Weights for Chronic Mercury Intoxication Resulting from Gold Mining Activities: Results from an Online Pairwise Comparisons Survey
title_sort disability weights for chronic mercury intoxication resulting from gold mining activities: results from an online pairwise comparisons survey
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295308/
https://www.ncbi.nlm.nih.gov/pubmed/28075395
http://dx.doi.org/10.3390/ijerph14010057
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