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Spatial learning and memory impairments are associated with increased neuronal activity in 5XFAD mouse as measured by manganese-enhanced magnetic resonance imaging

Dysfunction of neuronal activity is a major and early contributor to cognitive impairment in Alzheimer's disease (AD). To investigate neuronal activity alterations at early stage of AD, we encompassed behavioral testing and in vivo manganese-enhanced magnetic resonance imaging (MEMRI) in 5XFAD...

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Detalles Bibliográficos
Autores principales:	Tang, Xiang, Wu, Di, Gu, Li-Hua, Nie, Bin-Bin, Qi, Xin-Yang, Wang, Yan-Juan, Wu, Fang-Fang, Li, Xiao-Li, Bai, Feng, Chen, Xiao-Chun, Xu, Lin, Ren, Qing-Guo, Zhang, Zhi-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295372/ https://www.ncbi.nlm.nih.gov/pubmed/27542275 http://dx.doi.org/10.18632/oncotarget.11353

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