Expression and regulation of immune-modulatory enzyme indoleamine 2,3-dioxygenase (IDO) by human airway epithelial cells and its effect on T cell activation

Indoleamine 2,3-dioxygenase (IDO) catalyzes the degradation of tryptophan, which plays a critical role in immune suppression through regulating the production of a series of metabolites that are generally referred to as kynurenines. It has become increasingly clear that epithelial cells (ECs) play a...

Descripción completa

Detalles Bibliográficos
Autores principales: Aldajani, Wejdan A., Salazar, Fabián, Sewell, Herb F., Knox, Alan, Ghaemmaghami, Amir M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295376/
https://www.ncbi.nlm.nih.gov/pubmed/27613847
http://dx.doi.org/10.18632/oncotarget.11586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295376/
https://www.ncbi.nlm.nih.gov/pubmed/27613847
http://dx.doi.org/10.18632/oncotarget.11586

Ejemplares similares