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Expression and regulation of immune-modulatory enzyme indoleamine 2,3-dioxygenase (IDO) by human airway epithelial cells and its effect on T cell activation

Indoleamine 2,3-dioxygenase (IDO) catalyzes the degradation of tryptophan, which plays a critical role in immune suppression through regulating the production of a series of metabolites that are generally referred to as kynurenines. It has become increasingly clear that epithelial cells (ECs) play a...

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Detalles Bibliográficos
Autores principales:	Aldajani, Wejdan A., Salazar, Fabián, Sewell, Herb F., Knox, Alan, Ghaemmaghami, Amir M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295376/ https://www.ncbi.nlm.nih.gov/pubmed/27613847 http://dx.doi.org/10.18632/oncotarget.11586

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