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Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling

Fms-like tyrosine kinase (FLT3) is a frequently mutated oncogene in acute myeloid leukemia (AML). FLT3 inhibitors display promising results in a clinical setting, but patients relapse after short-term treatment due to the development of resistant disease. Therefore, a better understanding of FLT3 do...

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Detalles Bibliográficos
Autores principales:	Moharram, Sausan A., Chougule, Rohit A., Su, Xianwei, Li, Tianfeng, Sun, Jianmin, Zhao, Hui, Rönnstrand, Lars, Kazi, Julhash U.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295388/ https://www.ncbi.nlm.nih.gov/pubmed/27458164 http://dx.doi.org/10.18632/oncotarget.10760

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