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Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission
Fanconi anemia (FA) is a rare genetic disorder associated with bone-marrow failure, genome instability and cancer predisposition. Recently, we and others have demonstrated dysfunctional mitochondria with morphological alterations in FA cells accompanied by high reactive oxygen species (ROS) levels....
Autores principales: | Shyamsunder, Pavithra, Esner, Milan, Barvalia, Maunish, Wu, Yu Jun, Loja, Tomáš, Boon, Huat Bay, Lleonart, Matilde E., Verma, Rama S, Krejci, Lumir, Lyakhovich, Alex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295412/ https://www.ncbi.nlm.nih.gov/pubmed/27517150 http://dx.doi.org/10.18632/oncotarget.11161 |
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