Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through reduction in survival and invasion factors

We reported that knockdown of the antisense noncoding mitochondrial RNAs (ASncmtRNAs) induces apoptotic death of several human tumor cell lines, but not normal cells, suggesting this approach for selective therapy against different types of cancer. In order to translate these results to a preclinica...

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Detalles Bibliográficos
Autores principales: Lobos-González, Lorena, Silva, Verónica, Araya, Mariela, Restovic, Franko, Echenique, Javiera, Oliveira-Cruz, Luciana, Fitzpatrick, Christopher, Briones, Macarena, Villegas, Jaime, Villota, Claudio, Vidaurre, Soledad, Borgna, Vincenzo, Socias, Miguel, Valenzuela, Sebastián, Lopez, Constanza, Socias, Teresa, Varas, Manuel, Díaz, Jorge, Burzio, Luis O., Burzio, Verónica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295434/
https://www.ncbi.nlm.nih.gov/pubmed/27507060
http://dx.doi.org/10.18632/oncotarget.11110

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