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Growth factor progranulin promotes tumorigenesis of cervical cancer via PI3K/Akt/mTOR signaling pathway

Progranulin (PGRN) is an autocrine growth factor with tumorigenic roles in various tumors including cervical cancer. In this study, we investigated mammalian target of rapamycin (mTOR) signaling in response to PGRN induction and the contribution of the PGRN-stimulated PI3K/Akt/mTOR signaling pathway...

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Detalles Bibliográficos
Autores principales:	Feng, Tingting, Zheng, Lin, Liu, Feng, Xu, Xiaoying, Mao, Sheng, Wang, Xiao, Liu, Juan, Lu, Yi, Zhao, Weiming, Yu, Xiuping, Tang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295437/ https://www.ncbi.nlm.nih.gov/pubmed/27517315 http://dx.doi.org/10.18632/oncotarget.11126

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