Cargando…
DCUN1D3 activates SCF(SKP2) ubiquitin E3 ligase activity and cell cycle progression under UV damage
Our previous study showed that knockdown the endogenous expression of DCUN1D3 (also called SCCRO3 or DCNL3) blocked the S phase progression after UV irradiation. Here, we show that the silence of DCUN1D3 can increase the cyclin-dependent kinase inhibitor p27 protein levels after UV irradiation. Thro...
Autores principales: | Zhang, Shuai, Huang, Jing, Shi, Taiping, Hu, Fanlei, Zhang, Li, Zhou, Ping-Kun, Ma, Dalong, Ma, Teng, Qiu, Xiaoyan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295445/ https://www.ncbi.nlm.nih.gov/pubmed/27542266 http://dx.doi.org/10.18632/oncotarget.11302 |
Ejemplares similares
-
SCF-SKP2 E3 ubiquitin ligase links mTORC1/ER stress/ISR with YAP activation in murine renal cystogenesis
por: Panda, Dibyendu K., et al.
Publicado: (2022) -
The crystal structure of the Sgt1-Skp1 complex: the link between Hsp90 and both SCF E3 ubiquitin ligases and kinetochores
por: Willhoft, Oliver, et al.
Publicado: (2017) -
The SCF(Skp2) ubiquitin ligase complex modulates TRAIL-R2-induced apoptosis by regulating FLIP(L)
por: Roberts, Jamie Z., et al.
Publicado: (2020) -
Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligases
por: Zhou, Weihua, et al.
Publicado: (2013) -
Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL
por: Rodriguez, Sonia, et al.
Publicado: (2019)