Detection of the T790M mutation of EGFR in plasma of advanced non–small cell lung cancer patients with acquired resistance to tyrosine kinase inhibitors (West Japan oncology group 8014LTR study)

INTRODUCTION: Next-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have been developed to overcome resistance to earlier generations of such drugs mediated by a secondary T790M mutation of EGFR, but the performance of a second tumor biopsy to assess T790M mutatio...

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Detalles Bibliográficos
Autores principales: Takahama, Takayuki, Sakai, Kazuko, Takeda, Masayuki, Azuma, Koichi, Hida, Toyoaki, Hirabayashi, Masataka, Oguri, Tetsuya, Tanaka, Hiroshi, Ebi, Noriyuki, Sawa, Toshiyuki, Bessho, Akihiro, Tachihara, Motoko, Akamatsu, Hiroaki, Bandoh, Shuji, Himeji, Daisuke, Ohira, Tatsuo, Shimokawa, Mototsugu, Nakanishi, Yoichi, Nakagawa, Kazuhiko, Nishio, Kazuto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295446/
https://www.ncbi.nlm.nih.gov/pubmed/27542267
http://dx.doi.org/10.18632/oncotarget.11303

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