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Predictability of Genetic Interactions from Functional Gene Modules

Characterizing genetic interactions is crucial to understanding cellular and organismal response to gene-level perturbations. Such knowledge can inform the selection of candidate disease therapy targets, yet experimentally determining whether genes interact is technically nontrivial and time-consumi...

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Detalles Bibliográficos
Autores principales:	Young, Jonathan H., Marcotte, Edward M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2016
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295606/ https://www.ncbi.nlm.nih.gov/pubmed/28007839 http://dx.doi.org/10.1534/g3.116.035915

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