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TNFα alters occludin and cerebral endothelial permeability: Role of p38MAPK

Occludin is a key tight junction (TJ) protein in cerebral endothelial cells (CECs) playing an important role in modulating blood-brain barrier (BBB) functions. This protein (65kDa) has been shown to engage in many signaling pathways and phosphorylation by both tyrosine and threonine kinases. Despite...

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Detalles Bibliográficos
Autores principales: Ni, Yawen, Teng, Tao, Li, Runting, Simonyi, Agnes, Sun, Grace Y., Lee, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295672/
https://www.ncbi.nlm.nih.gov/pubmed/28170408
http://dx.doi.org/10.1371/journal.pone.0170346