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Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function
Sonic hedgehog (Shh) is a morphogen essential to the developing nervous system that continues to play an important role in adult life by contributing to cell proliferation and differentiation, maintaining blood-brain barrier integrity, and being cytoprotective against oxidative and excitotoxic stres...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295673/ https://www.ncbi.nlm.nih.gov/pubmed/28170441 http://dx.doi.org/10.1371/journal.pone.0171668 |